Data Science / Biochemistry Co-op (Summer-Fall 2026)

XGenomes is developing a radically new DNA sequencing technology that will revolutionize personalized healthcare. We watch single-molecule interactions at optical super-resolution, down to a few nanometers and use artificial intelligence to decode sequence and epigenetic states. 

We are looking for a data science intern with knowledge of biochemistry to join our team for a 6-month co-op in-person in Cambridge, MA, to work on simulations, data analysis and algorithms in conjunction with generating experimental data. 

We look forward to reading your application at this link

Responsibilities

  • Further development of super-resolution imaging data analysis pipeline
  • Conduct simulations and experiments to train machine learning models
  • Systematically analyze data to gain insights for optimizing the efficiency, reliability, and data quality of experiments
  • Work with our engineers to test and optimize assay scale-up

Essential Qualifications 

  • Ability to design, develop, test, and document software or data analysis tools 
  • Experience with bioinformatics, computational simulations, or analysis of large datasets, ideally in Julia, Python, or MATLAB
  • Foundation in biochemistry, including DNA/RNA molecular structure and interactions
  • Willingness to learn new skills, communicate across multi-disciplinary team, and document progress 

Nice-to-haves

  • Experience designing and performing molecular biology or chemistry lab experiments 
  • Familiarity with machine learning methods, including deep learning and image processing techniques
  • Ability to conduct in-depth literature reviews to identify technical solutions

Engineering Intern (Summer 2026)

XGenomes is developing a radically new DNA sequencing technology that will revolutionize personalized healthcare. We watch single-molecule interactions at optical super-resolution, down to a few nanometers and use artificial intelligence to decode sequence and epigenetic states. 

To scale up our prototype, we are looking for a mechatronics/mechanical/systems engineer to join our team for an in-person summer internship in Cambridge, MA. 

We look forward to reading your application at this link

Responsibilities

  • Develop and evaluate performance of heating and cooling systems for automated fluidics system for a prototype single-molecule DNA imaging platform
  • Integrate and control new fluidic components, such as pumps or thermocouples
  • Test system reliability across device subsystems including fluidics, hardware, and software
  • Implement work-flows and features in Python-based control software
  • Work with our biologists to improve experiment reliability and develop new features

Essential Qualifications

  • Massachusetts resident, or attending an accredited college/university located in Massachusetts or a Minority Serving Institution 
  • Experience building, validating, and troubleshooting heating and cooling systems
  • Ability to conduct calibration, testing, and maintenance of instrument subsystems, such as pumps, solenoids, thermocouples
  • Ability to use CAD tools (Solidworks, Fusion360) and 3D printing or laser cutting technologies to redesign and prototype instrument subsystems
  • Willingness to learn new skills, communicate across multi-disciplinary team, and document progress 

Nice-to-haves

  • Ability to develop embedded systems using Python, serial, Arduino, etc.
  • Experience with microfluidics theory and fabrication
  • Familiarity with DNA/RNA, biology, or chemical laboratory work

Don't see a fitting listed position?

XGenomes is interested in bringing aboard those with experience and interest in developing sequencing technologies, molecular diagnostics, or artificial intelligence, or in the broader bio-tools industry. Please send your CV and a brief statement of interest to hello@xgenomes.com.